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CpG ODN as an adjuvant arouses the vigor of B cells by relieving the negative regulation of surface...

CpG ODN as an adjuvant arouses the vigor of B cells by relieving the negative regulation of surface...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2522399912

CpG ODN as an adjuvant arouses the vigor of B cells by relieving the negative regulation of surface TLR9 to enhance the antibody response to vaccine

About this item

Full title

CpG ODN as an adjuvant arouses the vigor of B cells by relieving the negative regulation of surface TLR9 to enhance the antibody response to vaccine

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Applied microbiology and biotechnology, 2021-05, Vol.105 (10), p.4213-4224

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

The surface Toll-like receptor 9 (sTLR9) has been identified on the surface of the B cells and was presumed to be a negative regulator of B cell responses. CpG ODN, a TLR9 agonist, has been successfully used as an adjuvant of hepatitis B vaccine to enhance antibody responses. However, it is unknown whether the sTLR9 is involved in regulating the ac...

Alternative Titles

Full title

CpG ODN as an adjuvant arouses the vigor of B cells by relieving the negative regulation of surface TLR9 to enhance the antibody response to vaccine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2522399912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2522399912

Other Identifiers

ISSN

0175-7598

E-ISSN

1432-0614

DOI

10.1007/s00253-021-11316-9

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