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Safety and immunogenicity of high doses of quadrivalent influenza vaccine in children 6 months throu...

Safety and immunogenicity of high doses of quadrivalent influenza vaccine in children 6 months throu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2524302923

Safety and immunogenicity of high doses of quadrivalent influenza vaccine in children 6 months through <18 years of age: A randomized controlled phase II dose-finding trial

About this item

Full title

Safety and immunogenicity of high doses of quadrivalent influenza vaccine in children 6 months through <18 years of age: A randomized controlled phase II dose-finding trial

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2021-03, Vol.39 (11), p.1572-1582

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights:•Safety and immunogenicity of IIV4-HD was evaluated in USA and Canadian children 6 mos.-17 yrs. of age. •Three dose formulations of IIV4-HD (30 45, and 60 µg HA/strain/dose) were safe and well tolerated. •IIV4-HD 60 µg HA/strain/dose formulation generated higher immunogenicity compared to IIV4-SD. •Highest GMT ratios seen in children 6–3...

Alternative Titles

Full title

Safety and immunogenicity of high doses of quadrivalent influenza vaccine in children 6 months through <18 years of age: A randomized controlled phase II dose-finding trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2524302923

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2524302923

Other Identifiers

ISSN

0264-410X,1873-2518

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2021.02.014

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