Structure-based design approach of potential BCL-2 inhibitors for cancer chemotherapy
Structure-based design approach of potential BCL-2 inhibitors for cancer chemotherapy
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United States: Elsevier Ltd
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English
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United States: Elsevier Ltd
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AbstractB-cell lymphoma 2 (BCL-2) family is one of the chief regulators of cellular apoptosis. The intricate interactions between pro-apoptotic and anti-apoptotic genes of the BCL-2 family dictate the apoptotic balance of the cell. An overexpression of the anti-apoptotic members of BCL-2 is indicative of cell death evasion and cancer metastasis. Am...
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Structure-based design approach of potential BCL-2 inhibitors for cancer chemotherapy
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TN_cdi_proquest_miscellaneous_2524363312
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2524363312
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ISSN
0010-4825
E-ISSN
1879-0534
DOI
10.1016/j.compbiomed.2021.104455
