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SMARCAL1 loss and alternative lengthening of telomeres (ALT) are enriched in giant cell glioblastoma

SMARCAL1 loss and alternative lengthening of telomeres (ALT) are enriched in giant cell glioblastoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2539526520

SMARCAL1 loss and alternative lengthening of telomeres (ALT) are enriched in giant cell glioblastoma

About this item

Full title

SMARCAL1 loss and alternative lengthening of telomeres (ALT) are enriched in giant cell glioblastoma

Publisher

New York: Elsevier Inc

Journal title

Modern pathology, 2021-10, Vol.34 (10), p.1810-1819

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

Subsets of high-grade gliomas, including glioblastoma (GBM), are known to utilize the alternative lengthening of telomeres (ALT) pathway for telomere length maintenance. However, the telomere maintenance profile of one subtype of GBM—giant cell GBM—has not been extensively studied. Here, we investigated the prevalence of ALT, as well as ATRX and SM...

Alternative Titles

Full title

SMARCAL1 loss and alternative lengthening of telomeres (ALT) are enriched in giant cell glioblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2539526520

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2539526520

Other Identifiers

ISSN

0893-3952

E-ISSN

1530-0285

DOI

10.1038/s41379-021-00841-7

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