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Essential role of Notch/Hes1 signaling in postnatal pancreatic exocrine development

Essential role of Notch/Hes1 signaling in postnatal pancreatic exocrine development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2541319858

Essential role of Notch/Hes1 signaling in postnatal pancreatic exocrine development

About this item

Full title

Essential role of Notch/Hes1 signaling in postnatal pancreatic exocrine development

Publisher

Singapore: Springer Singapore

Journal title

Journal of gastroenterology, 2021-07, Vol.56 (7), p.673-687

Language

English

Formats

Publication information

Publisher

Singapore: Springer Singapore

More information

Scope and Contents

Contents

Background
Notch/Hes1 signaling has been shown to play a role in determining the fate of pancreatic progenitor cells. However, its function in postnatal pancreatic maturation is not fully elucidated.
Methods
We generated conditional
Hes1
knockout and/or Notch intracellular domain (NICD) overexpression mice in Ptf1a- or Pdx1-positive...

Alternative Titles

Full title

Essential role of Notch/Hes1 signaling in postnatal pancreatic exocrine development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2541319858

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2541319858

Other Identifiers

ISSN

0944-1174

E-ISSN

1435-5922

DOI

10.1007/s00535-021-01779-y

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