Therapeutic implications of menin inhibition in acute leukemias
Therapeutic implications of menin inhibition in acute leukemias
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Menin inhibitors are novel targeted agents currently in clinical development for the treatment of genetically defined subsets of acute leukemia. Menin has a tumor suppressor function in endocrine glands. Germline mutations in the gene encoding menin cause the multiple endocrine neoplasia type 1 (MEN1) syndrome, a hereditary condition associated wit...
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Full title
Therapeutic implications of menin inhibition in acute leukemias
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TN_cdi_proquest_miscellaneous_2541789295
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2541789295
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/s41375-021-01309-y