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Therapeutic implications of menin inhibition in acute leukemias

Therapeutic implications of menin inhibition in acute leukemias

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2541789295

Therapeutic implications of menin inhibition in acute leukemias

About this item

Full title

Therapeutic implications of menin inhibition in acute leukemias

Publisher

London: Nature Publishing Group UK

Journal title

Leukemia, 2021-09, Vol.35 (9), p.2482-2495

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Menin inhibitors are novel targeted agents currently in clinical development for the treatment of genetically defined subsets of acute leukemia. Menin has a tumor suppressor function in endocrine glands. Germline mutations in the gene encoding menin cause the multiple endocrine neoplasia type 1 (MEN1) syndrome, a hereditary condition associated wit...

Alternative Titles

Full title

Therapeutic implications of menin inhibition in acute leukemias

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2541789295

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2541789295

Other Identifiers

ISSN

0887-6924

E-ISSN

1476-5551

DOI

10.1038/s41375-021-01309-y

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