Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastat...
Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study
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Author / Creator
Lee, Chung-Han, MD , Shah, Amishi Yogesh, MD , Rasco, Drew, MD , Rao, Arpit, MD , Taylor, Matthew H, MD , Di Simone, Christopher, MD , Hsieh, James J, MD , Pinto, Alvaro, MD , Shaffer, David R, MD , Girones Sarrio, Regina, MD , Cohn, Allen Lee, MD , Vogelzang, Nicholas J, Prof , Bilen, Mehmet Asim, MD , Gunnestad Ribe, Sara, MD , Goksel, Musaberk, MD , Tennøe, Øyvind Krohn, MD , Richards, Donald, MD , Sweis, Randy F, MD , Courtright, Jay, MD , Heinrich, Daniel, MD , Jain, Sharad, MD , Wu, Jane, PhD , Schmidt, Emmett V, MD , Perini, Rodolfo F, MD , Kubiak, Peter, MD , Okpara, Chinyere E, PhD , Smith, Alan D, MD and Motzer, Robert J, MD
Publisher
London: Elsevier Ltd
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Language
English
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Publisher
London: Elsevier Ltd
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Contents
SummaryBackgroundDespite advances in the first-line treatment of metastatic renal cell carcinoma (RCC), there is an unmet need for options to address disease progression during or after treatment with immune checkpoint inhibitors (ICIs). Pembrolizumab and lenvatinib are active as monotherapies in RCC; thus, we aimed to evaluate the combination of l...
Alternative Titles
Full title
Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study
Authors, Artists and Contributors
Author / Creator
Shah, Amishi Yogesh, MD
Rasco, Drew, MD
Rao, Arpit, MD
Taylor, Matthew H, MD
Di Simone, Christopher, MD
Hsieh, James J, MD
Pinto, Alvaro, MD
Shaffer, David R, MD
Girones Sarrio, Regina, MD
Cohn, Allen Lee, MD
Vogelzang, Nicholas J, Prof
Bilen, Mehmet Asim, MD
Gunnestad Ribe, Sara, MD
Goksel, Musaberk, MD
Tennøe, Øyvind Krohn, MD
Richards, Donald, MD
Sweis, Randy F, MD
Courtright, Jay, MD
Heinrich, Daniel, MD
Jain, Sharad, MD
Wu, Jane, PhD
Schmidt, Emmett V, MD
Perini, Rodolfo F, MD
Kubiak, Peter, MD
Okpara, Chinyere E, PhD
Smith, Alan D, MD
Motzer, Robert J, MD
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2543453457
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2543453457
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(21)00241-2