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Claudin-1/4 as directly target gene of HIF-1α can feedback regulating HIF-1α by PI3K-AKT-mTOR and im...

Claudin-1/4 as directly target gene of HIF-1α can feedback regulating HIF-1α by PI3K-AKT-mTOR and im...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2553521492

Claudin-1/4 as directly target gene of HIF-1α can feedback regulating HIF-1α by PI3K-AKT-mTOR and impact the proliferation of esophageal squamous cell though Rho GTPase and p-JNK pathway

About this item

Full title

Claudin-1/4 as directly target gene of HIF-1α can feedback regulating HIF-1α by PI3K-AKT-mTOR and impact the proliferation of esophageal squamous cell though Rho GTPase and p-JNK pathway

Publisher

New York: Nature Publishing Group US

Journal title

Cancer gene therapy, 2022-06, Vol.29 (6), p.665-682

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Immunohistochemical microarray comprising 80 patients with esophageal squamous cell carcinoma (ESCC) and discovered that the expression of
CLDN1
and
CLDN4
were significantly higher in cancer tissues compared to para-cancerous tissues. Furthermore,
CLDN4
significantly affected the overall survival of cancer patients. When two ESCC...

Alternative Titles

Full title

Claudin-1/4 as directly target gene of HIF-1α can feedback regulating HIF-1α by PI3K-AKT-mTOR and impact the proliferation of esophageal squamous cell though Rho GTPase and p-JNK pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2553521492

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2553521492

Other Identifiers

ISSN

0929-1903,1476-5500

E-ISSN

1476-5500

DOI

10.1038/s41417-021-00328-2

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