NEU4 inhibits motility of HCC cells by cleaving sialic acids on CD44
NEU4 inhibits motility of HCC cells by cleaving sialic acids on CD44
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Author / Creator
Zhang, Xiaoqing , Dou, Peng , Akhtar, Muhammad Luqman , Liu, Fei , Hu, Xibo , Yang, Lijun , Yang, Depeng , Zhang, Xiaohan , Li, Yiqun , Qiao, Shupei , Li, Kai , Tang, Ran , Zhan, Chao , Ma, Yue , Cheng, Qixiang , Bai, Yan , Han, Fang , Nie, Huan and Li, Yu
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Hepatocellular carcinoma (HCC) is an extremely metastatic tumor. Sialic acids (SAs) are associated with cancer development and metastasis. NEU4 is a sialidase that removes SAs from glycoconjugates, while the function of the NEU4 in HCC has not been clearly explored. In our research, we found the NEU4 expression was significantly down-regulated in H...
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Full title
NEU4 inhibits motility of HCC cells by cleaving sialic acids on CD44
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TN_cdi_proquest_miscellaneous_2553525348
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2553525348
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ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/s41388-021-01955-7
