Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemother...
Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Tumor cells are often exposed to hypoxia because of the lower oxygen supply deep inside the tumor tissues. However, tumor cells survive in these severe conditions by adapting to hypoxic stress through the induction of hypoxia-inducible factor 1 (HIF-1) signaling. HIF-1 activation is responsible for the expression of numerous HIF-1 target genes, whi...
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Full title
Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy
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TN_cdi_proquest_miscellaneous_2557233705
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2557233705
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ISSN
0021-8820
E-ISSN
1881-1469
DOI
10.1038/s41429-021-00451-0
