Extensive phylogenies of human development inferred from somatic mutations
Extensive phylogenies of human development inferred from somatic mutations
About this item
Full title
Author / Creator
Coorens, Tim H. H. , Moore, Luiza , Robinson, Philip S. , Sanghvi, Rashesh , Christopher, Joseph , Hewinson, James , Przybilla, Moritz J. , Lawson, Andrew R. J. , Spencer Chapman, Michael , Cagan, Alex , Oliver, Thomas R. W. , Neville, Matthew D. C. , Hooks, Yvette , Noorani, Ayesha , Mitchell, Thomas J. , Fitzgerald, Rebecca C. , Campbell, Peter J. , Martincorena, Iñigo , Rahbari, Raheleh and Stratton, Michael R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Starting from the zygote, all cells in the human body continuously acquire mutations. Mutations shared between different cells imply a common progenitor and are thus naturally occurring markers for lineage tracing
1
,
2
. Here we reconstruct extensive phylogenies of normal tissues from three adult individuals using whole-genome sequenci...
Alternative Titles
Full title
Extensive phylogenies of human development inferred from somatic mutations
Authors, Artists and Contributors
Author / Creator
Moore, Luiza
Robinson, Philip S.
Sanghvi, Rashesh
Christopher, Joseph
Hewinson, James
Przybilla, Moritz J.
Lawson, Andrew R. J.
Spencer Chapman, Michael
Cagan, Alex
Oliver, Thomas R. W.
Neville, Matthew D. C.
Hooks, Yvette
Noorani, Ayesha
Mitchell, Thomas J.
Fitzgerald, Rebecca C.
Campbell, Peter J.
Martincorena, Iñigo
Rahbari, Raheleh
Stratton, Michael R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2564947649
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2564947649
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03790-y
