Programmed genome editing by a miniature CRISPR-Cas12f nuclease
Programmed genome editing by a miniature CRISPR-Cas12f nuclease
About this item
Full title
Author / Creator
Wu, Zhaowei , Zhang, Yifei , Yu, Haopeng , Pan, Deng , Wang, Yujue , Wang, Yannan , Li, Fan , Liu, Chang , Nan, Hao , Chen, Weizhong and Ji, Quanjiang
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The RNA-guided CRISPR-associated (Cas) nucleases are versatile tools for genome editing in various organisms. The large sizes of the commonly used Cas9 and Cas12a nucleases restrict their flexibility in therapeutic applications that use the cargo-size-limited adeno-associated virus delivery vehicle. More compact systems would thus offer more therap...
Alternative Titles
Full title
Programmed genome editing by a miniature CRISPR-Cas12f nuclease
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2569383744
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2569383744
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/s41589-021-00868-6
