Acalabrutinib, venetoclax, and obinutuzumab as frontline treatment for chronic lymphocytic leukaemia...
Acalabrutinib, venetoclax, and obinutuzumab as frontline treatment for chronic lymphocytic leukaemia: a single-arm, open-label, phase 2 study
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Author / Creator
Davids, Matthew S, MD , Lampson, Benjamin L, MD , Tyekucheva, Svitlana, PhD , Wang, Zixu, MS , Lowney, Jessica C, BS , Pazienza, Samantha, BS , Montegaard, Josie, NP , Patterson, Victoria, RN , Weinstock, Matthew, MD , Crombie, Jennifer L, MD , Ng, Samuel Y, MD , Kim, Austin I, MD , Jacobson, Caron A, MD , LaCasce, Ann S, MD , Armand, Philippe, MD , Arnason, Jon E, MD , Fisher, David C, MD and Brown, Jennifer R, Prof
Publisher
London: Elsevier Ltd
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Language
English
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Publisher
London: Elsevier Ltd
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Scope and Contents
Contents
SummaryBackgroundBoth continuous therapy with acalabrutinib and fixed-duration therapy with venetoclax–obinutuzumab are effective for previously untreated chronic lymphocytic leukaemia. We hypothesised that frontline time-limited, minimal residual disease (MRD)-guided triplet therapy with acalabrutinib, venetoclax, and obinutuzumab would induce dee...
Alternative Titles
Full title
Acalabrutinib, venetoclax, and obinutuzumab as frontline treatment for chronic lymphocytic leukaemia: a single-arm, open-label, phase 2 study
Authors, Artists and Contributors
Author / Creator
Lampson, Benjamin L, MD
Tyekucheva, Svitlana, PhD
Wang, Zixu, MS
Lowney, Jessica C, BS
Pazienza, Samantha, BS
Montegaard, Josie, NP
Patterson, Victoria, RN
Weinstock, Matthew, MD
Crombie, Jennifer L, MD
Ng, Samuel Y, MD
Kim, Austin I, MD
Jacobson, Caron A, MD
LaCasce, Ann S, MD
Armand, Philippe, MD
Arnason, Jon E, MD
Fisher, David C, MD
Brown, Jennifer R, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2574398293
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2574398293
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(21)00455-1
