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Oncogenic Ras expression increases cellular formate production

Oncogenic Ras expression increases cellular formate production

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2575377470

Oncogenic Ras expression increases cellular formate production

About this item

Full title

Oncogenic Ras expression increases cellular formate production

Publisher

Vienna: Springer Vienna

Journal title

Amino acids, 2021-10, Vol.53 (10), p.1589-1595

Language

English

Formats

Publication information

Publisher

Vienna: Springer Vienna

More information

Scope and Contents

Contents

One-carbon units, critical intermediates for cell growth, may be produced by a variety of means, one of which is via the production of formate. Excessive formate accumulation, known as formate overflow and a characteristic of oxidative cancer, has been observed in cancer cells. However, the basis for this high rate of formate production is unknown....

Alternative Titles

Full title

Oncogenic Ras expression increases cellular formate production

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2575377470

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2575377470

Other Identifiers

ISSN

0939-4451

E-ISSN

1438-2199

DOI

10.1007/s00726-021-03078-5

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