Macrophage IRX3 promotes diet-induced obesity and metabolic inflammation
Macrophage IRX3 promotes diet-induced obesity and metabolic inflammation
About this item
Full title
Author / Creator
Yao, Jingfei , Wu, Dongmei , Zhang, Chunyan , Yan, Ting , Zhao, Yiheng , Shen, Hongyu , Xue, Kaili , Huang, Xun , Wang, Zihao and Qiu, Yifu
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Metabolic inflammation is closely linked to obesity, and is implicated in the pathogenesis of metabolic diseases.
FTO
harbors the strongest genetic association with polygenic obesity, and
IRX3
mediates the effects of
FTO
on body weight. However, in what cells and how IRX3 carries out this control are poorly understood. Here we rep...
Alternative Titles
Full title
Macrophage IRX3 promotes diet-induced obesity and metabolic inflammation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2576652267
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2576652267
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-021-01023-y
