Weaker protection against tuberculosis in BCG-vaccinated male 129 S2 mice compared to females
Weaker protection against tuberculosis in BCG-vaccinated male 129 S2 mice compared to females
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Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Highlights•Protective efficacy of BCG was weaker in male 129 S2 mice than in females. •Male mice showed increased myeloid cell infiltration into lungs. •T cell responses were weaker in male mice. •Thus, sex plays a critical role in this experimental model of tuberculosis.
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Weaker protection against tuberculosis in BCG-vaccinated male 129 S2 mice compared to females
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TN_cdi_proquest_miscellaneous_2579097278
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2579097278
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2021.09.039