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Weaker protection against tuberculosis in BCG-vaccinated male 129 S2 mice compared to females

Weaker protection against tuberculosis in BCG-vaccinated male 129 S2 mice compared to females

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2579097278

Weaker protection against tuberculosis in BCG-vaccinated male 129 S2 mice compared to females

About this item

Full title

Weaker protection against tuberculosis in BCG-vaccinated male 129 S2 mice compared to females

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2021-12, Vol.39 (50), p.7253-7264

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights•Protective efficacy of BCG was weaker in male 129 S2 mice than in females. •Male mice showed increased myeloid cell infiltration into lungs. •T cell responses were weaker in male mice. •Thus, sex plays a critical role in this experimental model of tuberculosis.

Alternative Titles

Full title

Weaker protection against tuberculosis in BCG-vaccinated male 129 S2 mice compared to females

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2579097278

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2579097278

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2021.09.039

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