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Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis

Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2579378492

Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis

About this item

Full title

Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2021-12, Vol.17 (12), p.1314-1323

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Spindle position control is essential for cell fate determination and organogenesis. Early studies indicate the essential role of the evolutionarily conserved Gαi/LGN/NuMA network in spindle positioning. However, the regulatory mechanisms that couple astral microtubules dynamics to the spindle orientation remain elusive. Here we delineated a new mi...

Alternative Titles

Full title

Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2579378492

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2579378492

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-021-00875-7

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