The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea a...
The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea anemone Nematostella vectensis
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United States
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English
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United States
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In mammals, cyclic dinucleotides (CDNs) bind and activate STING to initiate an antiviral type I interferon response. CDNs and STING originated in bacteria and are present in most animals. By contrast, interferons are believed to have emerged in vertebrates; thus, the function of CDN signaling in invertebrates is unclear. Here, we use a CDN, 2'3' cy...
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The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea anemone Nematostella vectensis
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TN_cdi_proquest_miscellaneous_2610079529
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2610079529
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E-ISSN
1091-6490
DOI
10.1073/pnas.2109022118
