An RNA-cleaving threose nucleic acid enzyme capable of single point mutation discrimination
An RNA-cleaving threose nucleic acid enzyme capable of single point mutation discrimination
About this item
Full title
Author / Creator
Wang, Yueyao , Wang, Yao , Song, Dongfan , Sun, Xin , Li, Zhe , Chen, Jia-Yu and Yu, Hanyang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Threose nucleic acid has been considered a potential evolutionary progenitor of RNA because of its chemical simplicity, base pairing properties and capacity for higher-order functions such as folding and specific ligand binding. Here we report the in vitro selection of RNA-cleaving threose nucleic acid enzymes. One such enzyme, Tz1, catalyses a sit...
Alternative Titles
Full title
An RNA-cleaving threose nucleic acid enzyme capable of single point mutation discrimination
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2611657751
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2611657751
Other Identifiers
ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/s41557-021-00847-3
