Aging disrupts circadian gene regulation and function in macrophages
Aging disrupts circadian gene regulation and function in macrophages
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Aging is characterized by an increased vulnerability to infection and the development of inflammatory diseases, such as atherosclerosis, frailty, cancer and neurodegeneration. Here, we find that aging is associated with the loss of diurnally rhythmic innate immune responses, including monocyte trafficking from bone marrow to blood, response to lipo...
Alternative Titles
Full title
Aging disrupts circadian gene regulation and function in macrophages
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TN_cdi_proquest_miscellaneous_2614240715
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2614240715
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-021-01083-0
