Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine b...
Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors
About this item
Full title
Author / Creator
Publisher
England: Taylor & Francis
Journal title
Language
English
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Publication information
Publisher
England: Taylor & Francis
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Scope and Contents
Contents
α-Fluorinated chalcones were prepared and evaluated for their cell growth inhibitory properties against six human cancer cell lines. The most potent chalcone 4c demonstrated excellent selective toxicity against cancer cells versus normal human cells, with IC
50
values at nanomolar concentration ranges against 5 cancer cell lines. A further st...
Alternative Titles
Full title
Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors
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Record Identifier
TN_cdi_proquest_miscellaneous_2616599479
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2616599479
Other Identifiers
ISSN
1475-6366
E-ISSN
1475-6374
DOI
10.1080/14756366.2021.2014831
