APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis
APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis
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Publisher
England: Nature Publishing Group
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Language
English
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Publisher
England: Nature Publishing Group
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Contents
Endometriosis is a benign gynecologic condition, acting as a precursor of certain histological subtypes of ovarian cancers. The epithelial cells of endometriotic tissues and normal uterine endometrium accumulated somatic mutations in cancer-associated genes such as phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) and...
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APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis
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TN_cdi_proquest_miscellaneous_2619215037
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2619215037
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ISSN
1434-5161
E-ISSN
1435-232X
DOI
10.1038/s10038-021-01003-y