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APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis

APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2619215037

APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis

About this item

Full title

APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis

Publisher

England: Nature Publishing Group

Journal title

Journal of human genetics, 2022-06, Vol.67 (6), p.323-329

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

Endometriosis is a benign gynecologic condition, acting as a precursor of certain histological subtypes of ovarian cancers. The epithelial cells of endometriotic tissues and normal uterine endometrium accumulated somatic mutations in cancer-associated genes such as phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) and...

Alternative Titles

Full title

APOBEC mediated mutagenesis drives genomic heterogeneity in endometriosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2619215037

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2619215037

Other Identifiers

ISSN

1434-5161

E-ISSN

1435-232X

DOI

10.1038/s10038-021-01003-y

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