Shallow whole-genome sequencing: a useful, easy to apply molecular technique for CNA detection on FF...
Shallow whole-genome sequencing: a useful, easy to apply molecular technique for CNA detection on FFPE tumor tissue—a glioma-driven study
About this item
Full title
Author / Creator
Van der Eecken, Kim , Van der Linden, Malaïka , Raman, Lennart , Creytens, David , Dedeurwaerdere, Franceska , De Winne, Koen , Ferdinande, Liesbeth , Lammens, Martin , Menten, Björn , Rottiers, Isabelle , Van Gaever, Bram , Van den Broecke, Caroline , Van de Vijver, Koen , Van Roy, Nadine , Verbeke, Sofie and Van Dorpe, Jo
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Copy number alterations (CNAs) have increasingly become part of the diagnostic algorithm of glial tumors. Alterations such as homozygous deletion of
CDKN2A/B
, 7 +/ 10 - chromosome copy number changes or
EGFR
amplification are predictive of a poor prognosis. The codeletion of chromosome arms 1p and 19q, typically associated with oligode...
Alternative Titles
Full title
Shallow whole-genome sequencing: a useful, easy to apply molecular technique for CNA detection on FFPE tumor tissue—a glioma-driven study
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2620772711
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2620772711
Other Identifiers
ISSN
0945-6317
E-ISSN
1432-2307
DOI
10.1007/s00428-022-03268-w
