IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transiti...
IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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During inflammation, Ly6C
hi
monocytes are rapidly mobilized from the bone marrow (BM) and are recruited into inflamed tissues, where they undergo monocyte-to-phagocyte transition (MTPT). The in vivo developmental trajectories of the MTPT and the contribution of individual cytokines to this process remain unclear. Here, we used a murine model...
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IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation
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TN_cdi_proquest_miscellaneous_2624657557
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2624657557
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1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-021-01117-7