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IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transiti...

IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transiti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2624657557

IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation

About this item

Full title

IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2022-02, Vol.23 (2), p.217-228

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

During inflammation, Ly6C
hi
monocytes are rapidly mobilized from the bone marrow (BM) and are recruited into inflamed tissues, where they undergo monocyte-to-phagocyte transition (MTPT). The in vivo developmental trajectories of the MTPT and the contribution of individual cytokines to this process remain unclear. Here, we used a murine model...

Alternative Titles

Full title

IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2624657557

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2624657557

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/s41590-021-01117-7

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