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Differences in Cerebral Distribution between Imipramine and Paroxetine via Membrane Transporters at...

Differences in Cerebral Distribution between Imipramine and Paroxetine via Membrane Transporters at...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2625266223

Differences in Cerebral Distribution between Imipramine and Paroxetine via Membrane Transporters at the Rat Blood-Brain Barrier

About this item

Full title

Differences in Cerebral Distribution between Imipramine and Paroxetine via Membrane Transporters at the Rat Blood-Brain Barrier

Publisher

New York: Springer US

Journal title

Pharmaceutical research, 2022-02, Vol.39 (2), p.223-237

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Purpose
The present study aimed to elucidate the transport properties of imipramine and paroxetine, which are the antidepressants, across the blood-brain barrier (BBB) in rats.
Methods
In vivo influx and efflux transport of imipramine and paroxetine across the BBB were tested using integration plot analysis and a combination of brain efflu...

Alternative Titles

Full title

Differences in Cerebral Distribution between Imipramine and Paroxetine via Membrane Transporters at the Rat Blood-Brain Barrier

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2625266223

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2625266223

Other Identifiers

ISSN

0724-8741

E-ISSN

1573-904X

DOI

10.1007/s11095-022-03179-0

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