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Structure and receptor recognition by the Lassa virus spike complex

Structure and receptor recognition by the Lassa virus spike complex

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2629853060

Structure and receptor recognition by the Lassa virus spike complex

About this item

Full title

Structure and receptor recognition by the Lassa virus spike complex

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2022-03, Vol.603 (7899), p.174-179

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Lassa virus (LASV) is a human pathogen, causing substantial morbidity and mortality
1
,
2
. Similar to other
Arenaviridae
, it presents a class-I spike complex on its surface that facilitates cell entry. The virus’s cellular receptor is matriglycan, a linear carbohydrate that is present on α-dystroglycan
3
,
4
, but th...

Alternative Titles

Full title

Structure and receptor recognition by the Lassa virus spike complex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2629853060

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2629853060

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-022-04429-2

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