Structure and receptor recognition by the Lassa virus spike complex
Structure and receptor recognition by the Lassa virus spike complex
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Lassa virus (LASV) is a human pathogen, causing substantial morbidity and mortality
1
,
2
. Similar to other
Arenaviridae
, it presents a class-I spike complex on its surface that facilitates cell entry. The virus’s cellular receptor is matriglycan, a linear carbohydrate that is present on α-dystroglycan
3
,
4
, but th...
Alternative Titles
Full title
Structure and receptor recognition by the Lassa virus spike complex
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TN_cdi_proquest_miscellaneous_2629853060
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2629853060
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04429-2