Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin
Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin
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Author / Creator
Ju, Haiyan , Zhang, Chuanbo , He, Shifan , Nan, Weihua and Lu, Wenyu
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
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Scope and Contents
Contents
Forskolin, one of the primary active metabolites of labdane-type diterpenoids, exhibits significant medicinal value, such as anticancer, antiasthmatic, and antihypertensive activities. In this study, we constructed a
Saccharomyces cerevisiae
cell factory that efficiently produced forskolin. First, a chassis strain that can accumulate 145.8 mg...
Alternative Titles
Full title
Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2635244224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2635244224
Other Identifiers
ISSN
0175-7598
E-ISSN
1432-0614
DOI
10.1007/s00253-022-11819-z