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Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin

Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2635244224

Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin

About this item

Full title

Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Applied microbiology and biotechnology, 2022-03, Vol.106 (5-6), p.1933-1944

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Forskolin, one of the primary active metabolites of labdane-type diterpenoids, exhibits significant medicinal value, such as anticancer, antiasthmatic, and antihypertensive activities. In this study, we constructed a
Saccharomyces cerevisiae
cell factory that efficiently produced forskolin. First, a chassis strain that can accumulate 145.8 mg...

Alternative Titles

Full title

Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2635244224

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2635244224

Other Identifiers

ISSN

0175-7598

E-ISSN

1432-0614

DOI

10.1007/s00253-022-11819-z

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