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Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations du...

Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations du...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2641863630

Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations during Dropping

About this item

Full title

Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations during Dropping

Publisher

New York: Springer US

Journal title

Pharmaceutical research, 2022-04, Vol.39 (4), p.795-803

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Purposes
This article describes an interesting phenomenon in which optimized freeze-dried (FD) biopharmaceutical formulations are generally more prone to degradation than their liquid counterparts during dropping and proposes an underlying cause for this surprising phenomenon.
Methods
Two monoclonal antibodies (mAbs) and a fusion protein (...

Alternative Titles

Full title

Freeze-Dried Biopharmaceutical Formulations are Surprisingly Less Stable than Liquid Formulations during Dropping

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2641863630

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2641863630

Other Identifiers

ISSN

0724-8741

E-ISSN

1573-904X

DOI

10.1007/s11095-022-03235-9

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