De-escalated neoadjuvant pertuzumab plus trastuzumab therapy with or without weekly paclitaxel in HE...
De-escalated neoadjuvant pertuzumab plus trastuzumab therapy with or without weekly paclitaxel in HER2-positive, hormone receptor-negative, early breast cancer (WSG-ADAPT-HER2+/HR–): survival outcomes from a multicentre, open-label, randomised, phase 2 trial
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Author / Creator
Nitz, Ulrike, Prof , Gluz, Oleg, MD , Graeser, Monika, MD , Christgen, Matthias, Prof , Kuemmel, Sherko, PhD , Grischke, Eva-Maria, Prof , Braun, Michael, Prof , Augustin, Doris, MD , Potenberg, Jochem, MD , Krauss, Katja, MD , Schumacher, Claudia, MD , Forstbauer, Helmut, MD , Reimer, Toralf, Prof , Stefek, Andrea, MD , Fischer, Hans Holger, MD , Pelz, Enrico, MD , zu Eulenburg, Christine, PhD , Kates, Ronald, PhD , Wuerstlein, Rachel, PD MD , Kreipe, Hans Heinrich, Prof , Harbeck, Nadia, Prof and WSG-ADAPT investigators
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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More information
Scope and Contents
Contents
SummaryBackgroundSeveral de-escalation neoadjuvant strategies have been investigated to reduce the use of chemotherapy in HER2-positive early breast cancer using pathological complete response as a surrogate endpoint; there are few survival data from these trials. Here, we report 5-year survival data in the WSG-ADAPT-HER2+/HR– trial and address the...
Alternative Titles
Full title
De-escalated neoadjuvant pertuzumab plus trastuzumab therapy with or without weekly paclitaxel in HER2-positive, hormone receptor-negative, early breast cancer (WSG-ADAPT-HER2+/HR–): survival outcomes from a multicentre, open-label, randomised, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Gluz, Oleg, MD
Graeser, Monika, MD
Christgen, Matthias, Prof
Kuemmel, Sherko, PhD
Grischke, Eva-Maria, Prof
Braun, Michael, Prof
Augustin, Doris, MD
Potenberg, Jochem, MD
Krauss, Katja, MD
Schumacher, Claudia, MD
Forstbauer, Helmut, MD
Reimer, Toralf, Prof
Stefek, Andrea, MD
Fischer, Hans Holger, MD
Pelz, Enrico, MD
zu Eulenburg, Christine, PhD
Kates, Ronald, PhD
Wuerstlein, Rachel, PD MD
Kreipe, Hans Heinrich, Prof
Harbeck, Nadia, Prof
WSG-ADAPT investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2649592251
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2649592251
Other Identifiers
ISSN
1470-2045,1474-5488
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(22)00159-0
