Cullin-9/p53 mediates HNRNPC degradation to inhibit erastin-induced ferroptosis and is blocked by MD...
Cullin-9/p53 mediates HNRNPC degradation to inhibit erastin-induced ferroptosis and is blocked by MDM2 inhibition in colorectal cancer
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Author / Creator
Yang, Lv , WenTao, Tang , ZhiYuan, Zhang , Qi, Lin , YuXiang, Luo , Peng, Zheng , Ke, Li , XiaoNa, Jia , YuZhi, Pang , MeiLing, Ji , QingYang, Feng , GuoDong, He , YueXiang, Wang and JianMin, Xu
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Colorectal cancer (CRC) is the leading cause of cancer associated death worldwide. Ferroptosis is a newly defined form of regulated cell death characterized by the accumulation of lipid hydroperoxides and exerts an increased attention for cancer treatment. However, little is known about ferroptosis in CRC. In this study, through whole genome sequen...
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Full title
Cullin-9/p53 mediates HNRNPC degradation to inhibit erastin-induced ferroptosis and is blocked by MDM2 inhibition in colorectal cancer
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Record Identifier
TN_cdi_proquest_miscellaneous_2659605194
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2659605194
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02284-z
