EZH2 inhibitor tazemetostat in patients with relapsed or refractory, BAP1-inactivated malignant pleu...
EZH2 inhibitor tazemetostat in patients with relapsed or refractory, BAP1-inactivated malignant pleural mesothelioma: a multicentre, open-label, phase 2 study
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Author / Creator
Zauderer, Marjorie G, MD , Szlosarek, Peter W, Prof , Le Moulec, Sylvestre, MD , Popat, Sanjay, Prof , Taylor, Paul, MBChB , Planchard, David, MD , Scherpereel, Arnaud, Prof , Koczywas, Marianna, MD , Forster, Martin, MD , Cameron, Robert B, Prof , Peikert, Tobias, MD , Argon, Evren Kocabaş, DVM , Michaud, Neil R, PhD , Szanto, Attila, MD , Yang, Jay, PhD , Chen, Yingxue, PhD , Kansra, Vikram, PhD , Agarwal, Shefali, MD and Fennell, Dean A, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
SummaryBackgroundTreatment options for malignant pleural mesothelioma are scarce. Tazemetostat, a selective oral enhancer of zeste homolog 2 (EZH2) inhibitor, has shown antitumour activity in several haematological cancers and solid tumours. We aimed to evaluate the anti-tumour activity and safety of tazemetostat in patients with measurable relapse...
Alternative Titles
Full title
EZH2 inhibitor tazemetostat in patients with relapsed or refractory, BAP1-inactivated malignant pleural mesothelioma: a multicentre, open-label, phase 2 study
Authors, Artists and Contributors
Author / Creator
Szlosarek, Peter W, Prof
Le Moulec, Sylvestre, MD
Popat, Sanjay, Prof
Taylor, Paul, MBChB
Planchard, David, MD
Scherpereel, Arnaud, Prof
Koczywas, Marianna, MD
Forster, Martin, MD
Cameron, Robert B, Prof
Peikert, Tobias, MD
Argon, Evren Kocabaş, DVM
Michaud, Neil R, PhD
Szanto, Attila, MD
Yang, Jay, PhD
Chen, Yingxue, PhD
Kansra, Vikram, PhD
Agarwal, Shefali, MD
Fennell, Dean A, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2667792408
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2667792408
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(22)00277-7
