High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic dise...
High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease
About this item
Full title
Author / Creator
Tcheandjieu, Catherine , Xiao, Ke , Tejeda, Helio , Lynch, Julie A. , Ruotsalainen, Sanni , Bellomo, Tiffany , Palnati, Madhuri , Judy, Renae , Klarin, Derek , Kember, Rachel L. , Verma, Shefali , Palotie, Aarno , Daly, Mark , Ritchie, Marylyn , Rader, Daniel J. , Rivas, Manuel A. , Assimes, Themistocles , Tsao, Philip , Damrauer, Scott , Priest, James R. , FinnGen Project , Genome Informatics , Analytical Genomics and Data Science , Regeneron Genetics Center , VA Million Veterans Program , RGC Management and Leadership Team , Sequencing and Lab Operations , Clinical Informatics and Research Program Management & Strategic Initiatives
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Enlargement of the aorta is an important risk factor for aortic aneurysm and dissection, a leading cause of morbidity in the developed world. Here we performed automated extraction of ascending aortic diameter from cardiac magnetic resonance images of 36,021 individuals from the UK Biobank, followed by genome-wide association. We identified lead va...
Alternative Titles
Full title
High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease
Authors, Artists and Contributors
Author / Creator
Xiao, Ke
Tejeda, Helio
Lynch, Julie A.
Ruotsalainen, Sanni
Bellomo, Tiffany
Palnati, Madhuri
Judy, Renae
Klarin, Derek
Kember, Rachel L.
Verma, Shefali
Palotie, Aarno
Daly, Mark
Ritchie, Marylyn
Rader, Daniel J.
Rivas, Manuel A.
Assimes, Themistocles
Tsao, Philip
Damrauer, Scott
Priest, James R.
FinnGen Project
Genome Informatics
Analytical Genomics and Data Science
Regeneron Genetics Center
VA Million Veterans Program
RGC Management and Leadership Team
Sequencing and Lab Operations
Clinical Informatics
Research Program Management & Strategic Initiatives
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2672318528
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2672318528
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-022-01070-7
