sVCAM1 in the Hippocampus Contributes to Postoperative Cognitive Dysfunction in Mice by Inducing Mic...
sVCAM1 in the Hippocampus Contributes to Postoperative Cognitive Dysfunction in Mice by Inducing Microglial Activation Through the VLA-4 Receptor
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Author / Creator
Li, Chenglong , Li, Qi , Liu, Shuai , Li, Jiaying , Yu, Wei , Li, Yan , Zhang, Ruirui and Qi, Sihua
Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Contents
Postoperative cognitive dysfunction (POCD) is a severe postsurgical complication, but its underlying mechanisms remain unclear. Neuroinflammation mediated by microglial activation plays a major role in POCD pathophysiology. Upregulation of vascular cell adhesion molecule 1 (VCAM1) on brain endothelial cells is closely correlated with microglial act...
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Full title
sVCAM1 in the Hippocampus Contributes to Postoperative Cognitive Dysfunction in Mice by Inducing Microglial Activation Through the VLA-4 Receptor
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TN_cdi_proquest_miscellaneous_2679237928
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2679237928
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ISSN
0893-7648
E-ISSN
1559-1182
DOI
10.1007/s12035-022-02924-1