Spatial decrease of synaptic density in amnestic mild cognitive impairment follows the tau build-up...
Spatial decrease of synaptic density in amnestic mild cognitive impairment follows the tau build-up pattern
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Next to amyloid and tau, synaptic loss is a key pathological hallmark in Alzheimer’s disease, closely related to cognitive dysfunction and neurodegeneration. Tau is thought to cause synaptic loss, but this has not been experimentally verified in vivo. In a 2-year follow-up study, dual tracer PET-MR was performed in 12 amnestic MCI patients using
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Spatial decrease of synaptic density in amnestic mild cognitive impairment follows the tau build-up pattern
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TN_cdi_proquest_miscellaneous_2686056329
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2686056329
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ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/s41380-022-01672-x
