DNMT1-mediated epigenetic silencing of TRAF6 promotes prostate cancer tumorigenesis and metastasis b...
DNMT1-mediated epigenetic silencing of TRAF6 promotes prostate cancer tumorigenesis and metastasis by enhancing EZH2 stability
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Author / Creator
Li, Zhongwei , Li, Bingheng , Yu, Haiyuan , Wang, Pengfei , Wang, Wenwen , Hou, Pingfu , Li, Minle , Chu, Sufang , Zheng, Junnian , Mao, Lijun and Bai, Jin
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A plethora of studies have shown that both DNMT1 and EZH2 have great effects on the progression of a variety of cancers. However, it remains unclear whether the expression profiles of these two epigenetic enzymes are molecularly intertwined in prostate cancer (PC), especially in castration-resistant prostate cancer (CRPC). Here, we found that DNMT1...
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DNMT1-mediated epigenetic silencing of TRAF6 promotes prostate cancer tumorigenesis and metastasis by enhancing EZH2 stability
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TN_cdi_proquest_miscellaneous_2687726055
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2687726055
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02404-9
