scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks
scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Single-cell assay for transposase-accessible chromatin using sequencing (scATAC) shows great promise for studying cellular heterogeneity in epigenetic landscapes, but there remain important challenges in the analysis of scATAC data due to the inherent high dimensionality and sparsity. Here we introduce scBasset, a sequence-based convolutional neura...
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scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks
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TN_cdi_proquest_miscellaneous_2700313939
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2700313939
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/s41592-022-01562-8