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Prediction of Tissue Exposures of Meropenem, Colistin, and Sulbactam in Pediatrics Using Physiologic...

Prediction of Tissue Exposures of Meropenem, Colistin, and Sulbactam in Pediatrics Using Physiologic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2700639823

Prediction of Tissue Exposures of Meropenem, Colistin, and Sulbactam in Pediatrics Using Physiologically Based Pharmacokinetic Modeling

About this item

Full title

Prediction of Tissue Exposures of Meropenem, Colistin, and Sulbactam in Pediatrics Using Physiologically Based Pharmacokinetic Modeling

Publisher

Cham: Springer International Publishing

Journal title

Clinical pharmacokinetics, 2022-10, Vol.61 (10), p.1427-1441

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Background
The combination of polymyxins, meropenem, and sulbactam demonstrated efficacy against multi-drug-resistant bacillus
Acinetobacter baumannii
. These three antibiotics are commonly used against major blood, skin, lung, and heart muscle infections.
Objective
The objective of this study was to predict drug disposition and extr...

Alternative Titles

Full title

Prediction of Tissue Exposures of Meropenem, Colistin, and Sulbactam in Pediatrics Using Physiologically Based Pharmacokinetic Modeling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2700639823

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2700639823

Other Identifiers

ISSN

0312-5963

E-ISSN

1179-1926

DOI

10.1007/s40262-022-01161-y

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