Clinical Pharmacokinetic Monitoring of Free Valproic Acid Levels: A Systematic Review
Clinical Pharmacokinetic Monitoring of Free Valproic Acid Levels: A Systematic Review
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Cham: Springer International Publishing
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Language
English
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Publisher
Cham: Springer International Publishing
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Background
Current guidelines recommend therapeutic drug monitoring as a critical component of valproic acid (VPA) therapy. Due to high protein binding, the active unbound (free) portion of VPA can be misrepresented by total VPA serum levels in certain clinical scenarios. Monitoring free VPA serum levels may be warranted when assessing the clini...
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Full title
Clinical Pharmacokinetic Monitoring of Free Valproic Acid Levels: A Systematic Review
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TN_cdi_proquest_miscellaneous_2708260039
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2708260039
Other Identifiers
ISSN
0312-5963
E-ISSN
1179-1926
DOI
10.1007/s40262-022-01171-w
