USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for...
USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Ubiquitin specific peptidase 7 (USP7) is a deubiquitinating enzyme (DUB) that removes ubiquitin tags from specific target protein substrates in order to alter their degradation rate, sub-cellular localization, interaction, and activity. The induction of apoptosis upon USP7 inhibition is well established in cancer containing wild type p53, which ope...
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USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma
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TN_cdi_proquest_miscellaneous_2725190752
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2725190752
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02486-5
