UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquit...
UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination
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Author / Creator
Ma, Meilin , Zhang, Changhui , Cao, Rong , Tang, Dongmei , Sang, Xiongbo , Zou, Sailan , Wang, Xiuxuan , Xu, Haixia , Liu, Geng , Dai, Lunzhi , Tian, Yan , Gao, Xiang and Fu, Xianghui
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Cancer cells rely on heightened protein quality control mechanisms, including the ubiquitin-proteosome system that is predominantly driven by ubiquitination comprising E1, E2, and E3 trienzyme cascades. Although E3s have been extensively studied, the implication of E2s in tumorigenesis is poorly defined. Here we reveal a critical E2 in the pathogen...
Alternative Titles
Full title
UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination
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Record Identifier
TN_cdi_proquest_miscellaneous_2727638446
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2727638446
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-022-02509-1
