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Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requir...

Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requir...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2729027381

Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting

About this item

Full title

Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Supportive care in cancer, 2022-12, Vol.30 (12), p.9991-9999

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
Chemotherapy-induced nausea and vomiting (CINV) are common side effects in pediatric oncology treatment. Besides 5-HT
3
-antagonists, both dexamethasone and aprepitant are cornerstone drugs in controlling these side effects. Based on results of adult studies, the dexamethasone dose is reduced by 50% when combined with aprepitant, b...

Alternative Titles

Full title

Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2729027381

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2729027381

Other Identifiers

ISSN

0941-4355,1433-7339

E-ISSN

1433-7339

DOI

10.1007/s00520-022-07423-6

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