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Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through r...

Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2735168922

Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through reactive oxygen species accumulation and gasdermin E cleavage in breast cancer cells

About this item

Full title

Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through reactive oxygen species accumulation and gasdermin E cleavage in breast cancer cells

Publisher

New York: Springer US

Journal title

Medical oncology (Northwood, London, England), 2022-11, Vol.40 (1), p.11-11, Article 11

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is selectively lethal to cancer cells and harmless to normal cells, making it a potential agent for cancer therapy. However, some breast cancer cells are resistant to TRAIL. This study revealed that andrographolide (Andro), an extract from
Andrographis paniculate
, a natural comp...

Alternative Titles

Full title

Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through reactive oxygen species accumulation and gasdermin E cleavage in breast cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2735168922

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2735168922

Other Identifiers

ISSN

1559-131X,1357-0560

E-ISSN

1559-131X

DOI

10.1007/s12032-022-01878-7

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