Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through r...
Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through reactive oxygen species accumulation and gasdermin E cleavage in breast cancer cells
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Author / Creator
Wang, Yueyuan , Huang, Dan , Song, Tingting , Qi, Xiaoyan , Li, Mingxi , Zhang, Hui , Liu, Yang and Yang, Ming
Publisher
New York: Springer US
Journal title
Language
English
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Publication information
Publisher
New York: Springer US
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Scope and Contents
Contents
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is selectively lethal to cancer cells and harmless to normal cells, making it a potential agent for cancer therapy. However, some breast cancer cells are resistant to TRAIL. This study revealed that andrographolide (Andro), an extract from
Andrographis paniculate
, a natural comp...
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Full title
Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through reactive oxygen species accumulation and gasdermin E cleavage in breast cancer cells
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2735168922
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2735168922
Other Identifiers
ISSN
1559-131X,1357-0560
E-ISSN
1559-131X
DOI
10.1007/s12032-022-01878-7