Antiviral signalling by a cyclic nucleotide activated CRISPR protease
Antiviral signalling by a cyclic nucleotide activated CRISPR protease
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Author / Creator
Rouillon, Christophe , Schneberger, Niels , Chi, Haotian , Blumenstock, Katja , Da Vela, Stefano , Ackermann, Katrin , Moecking, Jonas , Peter, Martin F. , Boenigk, Wolfgang , Seifert, Reinhard , Bode, Bela E. , Schmid-Burgk, Jonathan L. , Svergun, Dmitri , Geyer, Matthias , White, Malcolm F. and Hagelueken, Gregor
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
CRISPR defence systems such as the well-known DNA-targeting Cas9 and the RNA-targeting type III systems are widespread in prokaryotes
1
,
2
. The latter orchestrates a complex antiviral response that is initiated through the synthesis of cyclic oligoadenylates after recognition of foreign RNA
3
–
5
. Among the large set of p...
Alternative Titles
Full title
Antiviral signalling by a cyclic nucleotide activated CRISPR protease
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2740514013
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2740514013
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-05571-7
