Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia
Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia
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United States: Oxford University Press
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Language
English
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United States: Oxford University Press
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Abstract
Hypoxia-inducible factor (HIF)1α is a transcription factor involved in cellular metabolism and regulation of immune cell effector functions. Here, we studied the role of HIF1α in myeloid cells during pneumonia caused by the major causative pathogen, Streptococcus pneumoniae (Spneu). Mice deficient for HIF1α in myeloid cells (LysMcreHif1...
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Full title
Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia
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TN_cdi_proquest_miscellaneous_2756122142
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2756122142
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ISSN
2049-632X
E-ISSN
2049-632X
DOI
10.1093/femspd/ftac047