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Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia

Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2756122142

Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia

About this item

Full title

Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia

Publisher

United States: Oxford University Press

Journal title

Pathogens and disease, 2023-01, Vol.81

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

Abstract
Hypoxia-inducible factor (HIF)1α is a transcription factor involved in cellular metabolism and regulation of immune cell effector functions. Here, we studied the role of HIF1α in myeloid cells during pneumonia caused by the major causative pathogen, Streptococcus pneumoniae (Spneu). Mice deficient for HIF1α in myeloid cells (LysMcreHif1...

Alternative Titles

Full title

Role of Hypoxia-inducible factor 1α in host defense during pneumococcal pneumonia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2756122142

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2756122142

Other Identifiers

ISSN

2049-632X

E-ISSN

2049-632X

DOI

10.1093/femspd/ftac047

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