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Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at...

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2758354503

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial

About this item

Full title

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial

Author / Creator

Hobbs, F D Richard , Rahman, Najib M , Hayward, Gail , Richards, Duncan B , Lowe, David M , Standing, Joseph F , Breuer, Judith , Khoo, Saye , Petrou, Stavros , Hood, Kerenza , Nguyen-Van-Tam, Jonathan S , Patel, Mahendra G , Saville, Benjamin R , Marion, Joe , Ogburn, Emma , Allen, Julie , Francis, Nick , Evans, Philip , Holmes, Jane , Harris, Victoria , van Hecke, Oliver , Detry, Michelle A , Saunders, Christina T , Fitzgerald, Mark , Mwandigha, Lazaro , Galal, Ushma , Mort, Sam , Hart, Nigel D , Butler, Daniel , McKenna, Micheal , Lavallee, Layla , Cureton, Lucy , Benysek, Magdalena , Davies, Jennifer C , Raymundo-Wood, Ivy , Ustianowski, Andrew , Carson-Stevens, Andrew , Yu, Ly-Mee , Little, Paul , Ahmed, Tanveer , Allcock, Damien , Beltran-Martinez, Adrian , Brennan, Laura , Burns, Gerard , Butler, Mike , Cheng, Zelda , Danson, Ruth , de Kare-Silver, Nigel , Dhasmana, Devesh , Dickson, Jon , Engamba, Serge , Fisher, Stacey , Fox, Robin , Frost, Eve , Ghosh, Sarit , Goodman, Anna , Granier, Steve , Howell, Aleksandra , Hussain, Iqbal , Hutchinson, Simon , Imlach, Marie , Irving, Greg , Jacobsen, Nicholas , Kennard, James , Khan, Umar , Krasucki, Christopher , Law, Tom , Lee, Rem , Lester, Nicola , Lewis, David , Lunn, James , Mackintosh, Claire I. , Mathukia, Mehul , Moore, Patrick , Morton, Seb , Murphy, Daniel , Nally, Rhiannon , Ndukauba, Chinonso , Ogundapo, Olufunto , Okeke, Henry , Patel, Amit , Penfold, Ruth , Popoola, Olajide , Pora, Alexander , Prasad, Vibhore , Razzaq, Omair , Richardson, Scot , Safa, Afsana , Sehdev, Satash , Sevenoaks, Tamsin , Short, Vanessa , Singh, Ivor , Thalasselis, Chris , Wilson, Pete , Wingfield, David , Wong, Michael , Woodall, Maximillian N J , Woods, Sharon , Yong, Joanna , Yongblah, Francis and PANORAMIC Trial Collaborative Group

Publisher

England: Elsevier Ltd

Journal title

The Lancet (British edition), 2023-01, Vol.401 (10373), p.281-293

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the community at increased risk of morbidity and mortality from COVID-19. We aimed to establish whether the addition of molnupiravir to usual care reduced hospital admissions and deaths a...

Alternative Titles

Full title

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial

Authors, Artists and Contributors

Author / Creator

Hobbs, F D Richard
Rahman, Najib M
Hayward, Gail
Richards, Duncan B
Lowe, David M
Standing, Joseph F
Breuer, Judith
Khoo, Saye
Petrou, Stavros
Hood, Kerenza
Nguyen-Van-Tam, Jonathan S
Patel, Mahendra G
Saville, Benjamin R
Marion, Joe
Ogburn, Emma
Allen, Julie
Francis, Nick
Evans, Philip
Holmes, Jane
Harris, Victoria
van Hecke, Oliver
Detry, Michelle A
Saunders, Christina T
Fitzgerald, Mark
Mwandigha, Lazaro
Galal, Ushma
Mort, Sam
Hart, Nigel D
Butler, Daniel
McKenna, Micheal
Lavallee, Layla
Cureton, Lucy
Benysek, Magdalena
Davies, Jennifer C
Raymundo-Wood, Ivy
Ustianowski, Andrew
Carson-Stevens, Andrew
Yu, Ly-Mee
Little, Paul
Ahmed, Tanveer
Allcock, Damien
Beltran-Martinez, Adrian
Brennan, Laura
Burns, Gerard
Butler, Mike
Cheng, Zelda
Danson, Ruth
de Kare-Silver, Nigel
Dhasmana, Devesh
Dickson, Jon
Engamba, Serge
Fisher, Stacey
Fox, Robin
Frost, Eve
Ghosh, Sarit
Goodman, Anna
Granier, Steve
Howell, Aleksandra
Hussain, Iqbal
Hutchinson, Simon
Imlach, Marie
Irving, Greg
Jacobsen, Nicholas
Kennard, James
Khan, Umar
Krasucki, Christopher
Law, Tom
Lee, Rem
Lester, Nicola
Lewis, David
Lunn, James
Mackintosh, Claire I.
Mathukia, Mehul
Moore, Patrick
Morton, Seb
Murphy, Daniel
Nally, Rhiannon
Ndukauba, Chinonso
Ogundapo, Olufunto
Okeke, Henry
Patel, Amit
Penfold, Ruth
Popoola, Olajide
Pora, Alexander
Prasad, Vibhore
Razzaq, Omair
Richardson, Scot
Safa, Afsana
Sehdev, Satash
Sevenoaks, Tamsin
Short, Vanessa
Singh, Ivor
Thalasselis, Chris
Wilson, Pete
Wingfield, David
Wong, Michael
Woodall, Maximillian N J
Woods, Sharon
Yong, Joanna
Yongblah, Francis
PANORAMIC Trial Collaborative Group

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2758354503

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2758354503

Other Identifiers

ISSN

0140-6736,1474-547X

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(22)02597-1

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