Gene of the month: PALB2
Gene of the month: PALB2
About this item
Full title
Author / Creator
Publisher
England: BMJ Publishing Group Ltd and Association of Clinical Pathologists
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and Association of Clinical Pathologists
Subjects
More information
Scope and Contents
Contents
The partner and localiser of BRCA2 (PALB2) gene, located on chromosome 16, functions as a tumour suppressor that plays a critical role in homologous recombination repair after DNA double-strand breaks. It encodes proteins involved in the BRCA2 and BRCA1, and RAD51 pathways. Heterozygous germline mutations in PALB2 have been implicated in the develo...
Alternative Titles
Full title
Gene of the month: PALB2
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2761179659
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2761179659
Other Identifiers
ISSN
0021-9746
E-ISSN
1472-4146
DOI
10.1136/jcp-2022-208461
