Selenylated Imidazo1,2-apyridine Induces Cell Senescence and Oxidative Stress in Chronic Myeloid Leu...
Selenylated Imidazo1,2-apyridine Induces Cell Senescence and Oxidative Stress in Chronic Myeloid Leukemia Cells
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Full title
Author / Creator
Burkner, Gabriella Teles , Dias, Dhébora Albuquerque , Souza, Kamylla Fernanda Souza de , Araújo, Anna Júlia Papa de , Basilio, Denise Caroline Luiz Soares , Jacobsen, Fernanda Tondello , Moraes, Ana Carolina Rabello de , Silva-Filho, Saulo Euclides , Cavalcante, Marcos Filipe de Oliveira , Moraes, Cassio Augusto de Oliveira , Saba, Sumbal , Macedo, Maria Lígia Rodrigues , Paredes-Gamero, Edgar Julian , Rafique, Jamal and Parisotto, Eduardo Benedetti
Journal title
Language
English
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Scope and Contents
Contents
Imidazo[1,2-a]pyridines (IPs) have been studied regarding drug development. The objective of this work was to evaluate the antileukemic capacity of IP derivatives by screening their ability as a pro-oxidant. IP derivatives were synthesized and oral bioavailability and toxicity were analyzed in silico. Redox screening was performed on human Kasumi,...
Alternative Titles
Full title
Selenylated Imidazo1,2-apyridine Induces Cell Senescence and Oxidative Stress in Chronic Myeloid Leukemia Cells
Authors, Artists and Contributors
Author / Creator
Dias, Dhébora Albuquerque
Souza, Kamylla Fernanda Souza de
Araújo, Anna Júlia Papa de
Basilio, Denise Caroline Luiz Soares
Jacobsen, Fernanda Tondello
Moraes, Ana Carolina Rabello de
Silva-Filho, Saulo Euclides
Cavalcante, Marcos Filipe de Oliveira
Moraes, Cassio Augusto de Oliveira
Saba, Sumbal
Macedo, Maria Lígia Rodrigues
Paredes-Gamero, Edgar Julian
Rafique, Jamal
Parisotto, Eduardo Benedetti
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2768245228
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2768245228
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules28020893
