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N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting...

N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2777406252

N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing

About this item

Full title

N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2023-03, Vol.42 (14), p.1101-1116

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Although N4-acetylcytidine (ac4C) modification affects the stability and translation of mRNA, it is unknown whether it exists in noncoding RNAs, and its biological function is unclear. Here, nucleotide-resolution method for profiling CTC-490G23.2 ac4C sites and gain- and loss-of-function experiments revealed that N-acetyltransferase 10 (NAT10) is r...

Alternative Titles

Full title

N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2777406252

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2777406252

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/s41388-023-02628-3

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