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A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the c...

A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2778973653

A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the cyclin D1–CDK4 interaction

About this item

Full title

A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the cyclin D1–CDK4 interaction

Publisher

New York: Springer US

Journal title

Breast cancer research and treatment, 2023-04, Vol.198 (3), p.555-568

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Background
Cyclin D1 overexpression may contribute to development of various cancers, including breast cancer, and thus may serve as a key cancer diagnostic marker and therapeutic target. In our previous study, we generated a cyclin D1-specific single-chain variable fragment antibody (ADκ) from a human semi-synthetic single-chain variable fragme...

Alternative Titles

Full title

A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the cyclin D1–CDK4 interaction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2778973653

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2778973653

Other Identifiers

ISSN

0167-6806

E-ISSN

1573-7217

DOI

10.1007/s10549-023-06866-7

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