A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the c...
A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the cyclin D1–CDK4 interaction
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Author / Creator
Zhao, Jialiang , Wu, Yan , Xiao, Tong , Cheng, Cheng , Zhang, Tong , Gao, Ziyang , Hu, Siyuan , Ren, Ze , Yu, Xinze , Yang, Fang and Li, Guiying
Publisher
New York: Springer US
Journal title
Language
English
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Publication information
Publisher
New York: Springer US
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Scope and Contents
Contents
Background
Cyclin D1 overexpression may contribute to development of various cancers, including breast cancer, and thus may serve as a key cancer diagnostic marker and therapeutic target. In our previous study, we generated a cyclin D1-specific single-chain variable fragment antibody (ADκ) from a human semi-synthetic single-chain variable fragme...
Alternative Titles
Full title
A specific anti-cyclin D1 intrabody represses breast cancer cell proliferation by interrupting the cyclin D1–CDK4 interaction
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2778973653
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2778973653
Other Identifiers
ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-023-06866-7