Classic Phytochemical Antioxidant and Lipoxygenase Inhibitor, Nordihydroguaiaretic Acid, Activates P...
Classic Phytochemical Antioxidant and Lipoxygenase Inhibitor, Nordihydroguaiaretic Acid, Activates Phospholipase D through Oxidant Signaling and Tyrosine Phosphorylation Leading to Cytotoxicity in Lung Vascular Endothelial Cells
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Author / Creator
Parinandi, Narasimham L. , Liaugminas, Alex , Oliver, Patrick J. , Varadharaj, Saradhadevi , Yenigalla, Anita , Elliott, Austin C. , Arutla, Sukruthi , Campbell, Steven J. , Kotha, Sainath R. , Sherwani, Shariq I. , Kutala, Vijay K. , McDaniel, Jodi C. , Maddipati, Krishna Rao , Kuppusamy, Periannan and Hund, Thomas J.
Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Contents
Nordihydroguaiaretic acid (NDGA), a dicatechol and phytochemical polyphenolic antioxidant and an established inhibitor of human arachidonic acid (AA) 5-lipoxygenase (LOX) and 15-LOX, is widely used to ascertain the role of LOXs in vascular endothelial cell (EC) function. As the modulatory effect of NDGA on phospholipase D (PLD), an important lipid...
Alternative Titles
Full title
Classic Phytochemical Antioxidant and Lipoxygenase Inhibitor, Nordihydroguaiaretic Acid, Activates Phospholipase D through Oxidant Signaling and Tyrosine Phosphorylation Leading to Cytotoxicity in Lung Vascular Endothelial Cells
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Record Identifier
TN_cdi_proquest_miscellaneous_2779348076
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2779348076
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ISSN
1085-9195
E-ISSN
1559-0283
DOI
10.1007/s12013-023-01128-1
